2014

December 10 2014
Onur:
Kinetic competition during the transcription cycle results in stochastic RNA processing
http://elifesciences.org/content/early/2014/10/01/eLife.03939
AND
Rapid and tunable post-translational coupling of genetic circuits
http://www.nature.com/nature/journal/v508/n7496/full/nature13238.html
 

December 3 2014
Kyle:
Topologically associating domains are stable units of replication-timing
http://www.nature.com/nature/journal/v515/n7527/full/nature13986.html

November 26 2014
Jon Sobel:
Circadian Enhancers Coordinate Multiple Phases of Rhythmic Gene Transcription in vivo
http://dx.doi.org/10.1016/j.cell.2014.10.022

November 19 2014
Jake:
Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways
http://elifesciences.org/content/3/e02626

November 12 2014
Ben:
Quantitative single-cell RNA-seq with unique molecular identifiers
http://www.nature.com/nmeth/journal/v11/n2/full/nmeth.2772.html

Validation of noise models for single-cell transcriptomics
http://www.nature.com/nmeth/journal/v11/n6/full/nmeth.2930.html

November 5 2014
Saeed:
Epigenetic Landscapes Explain Partially Reprogrammed Cells and identify Key Reprogramming Genes
http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1003734

 
October 29 2014
Jake:
Transcriptional diversity during lineage commitment of human blood progenitors
http://www.sciencemag.org/content/345/6204/1251033.full

October 15 2014
Kyle:
Enhancer RNA Facilitates NELF Release from Immediate Early Genes

http://www.sciencedirect.com/science/article/pii/S1097276514006789

 
October 8 2014
Jingkui:
Translation of pre-spliced RNAs in the nuclear compartment generates peptides for the MHC class I pathway
 
October 1 2014
Jérôme:
An atlas of active enhancers across human cell types and tissues. 
 
September 24 2014
Damien: 
Direct observation of frequency modulated transcription in single cells using light activation
Transcription Factors Modulate c-Fos Transcriptional Bursts 
 
September 16 2014
Kyle: 
Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions
Enhancer networks revealed by correlated DNAse hypersensitivity states of enhancers
 
September 9 2014
Jérôme: 
Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment
http://www.nature.com/ng/journal/v46/n2/full/ng.2871.html
Targeted Chromatin Capture (T2C): a novel high resolution high throughput method to detect genomic interactions and regulatory elements
 
July 16 2014
Kyle: 
Genome-scale functional characterization of Drosophila developmental enhancers in vivo
 
June 25 2014
Kyle: 
Machine learning helps identify CHRONO as a circadian clock component
A novel protein, CHRONO, functions as a core component of the mammalian circadian clock